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Odorless isocyanide chemistry: an integrated microfluidic system for a multistep reaction sequence.

Abstract
Can't smell this: An integrated continuous-flow microfluidic setup enables in situ generation, extraction, separation, and reaction of foul-smelling isocyanides with little exposure to the surroundings. Isocyanides were generated by dehydration of the corresponding N-substituted formamides, and several representative isocyanide-based organic reactions were successfully performed. DIPEA = N,N-diisopropylethylamine.
AuthorsSiddharth Sharma, Ram Awatar Maurya, Kyoung-Ik Min, Guan-Young Jeong, Dong-Pyo Kim
JournalAngewandte Chemie (International ed. in English) (Angew Chem Int Ed Engl) Vol. 52 Issue 29 Pg. 7564-8 (Jul 15 2013) ISSN: 1521-3773 [Electronic] Germany
PMID23780803 (Publication Type: Journal Article)
CopyrightCopyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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