[The effect of tetracycline therapy on the laboratory indices of chlamydia infection in Reiter's disease (preliminary report)].

Abstract

The authors studied the effect of tetracycline therapy (short and long courses) on the indices of chlamydia infection (antigens and antibodies) in Reiter's urogenous disease. The concentration of tetracycline in the blood serum and synovial fluid when administered in a daily dose of 2.0 g (single dose 0.5 g) was determined. It has been established that tetracycline exerts an inhibitory effect on the chlamydia infection not in all the patients suffering from Reiter's disease despite sufficient concentration of the antibiotic in biological fluids (blood serum, synovial fluid). Prolonged courses of tetracycline therapy proved most effective.

• Authors: A A Khamraev, V N Pankratova, N S Brodinova, O E Orlova, S V Shubin
• Journal: Revmatologiia (Moscow, Russia) (Revmatologiia (Mosk)) 1990 Jan-Mar Issue 1 Pg. 17-21 ISSN: 0233-7029 [Print] Russia (Federation)
• Vernacular Title: Vliianie tetratsiklinoterapii na laboratornye pokazateli khlamidiĭnoĭ infektsii pri bolezni Reĭtera (predvaritel'noe soobshchenie).
• PMID: 2377858 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antibodies, Bacterial
• Antigens, Bacterial
• Tetracycline

Topics

• Adolescent
• Adult
• Antibodies, Bacterial (analysis)
• Antigens, Bacterial (analysis)
• Arthritis, Reactive (drug therapy, immunology)
• Chlamydia Infections (drug therapy, immunology)
• Chlamydia trachomatis (immunology)
• Humans
• Male
• Middle Aged
• Tetracycline (therapeutic use)