Abstract | BACKGROUND: Screening for Hepatitis B and C during pregnancy may help to decide on appropriate antiviral therapy and the institution of steps to minimize vertical transmission to the newborn infants. METHODS: A cross-sectional study was conducted during November-December 2011 to investigate the seroprevalence and associated risk factors for markers of HBV ( hepatitis B surface antigen; HBsAg) and anti-HCV antibody among pregnant women at the Al-Thawra hospital in Sana'a, Yemen. Structured questionnaires were used to obtain sociodemographic obstetrics and medical data and sera were tested for HBsAg and anti-HCV. RESULTS: Of the 400 pregnant women enrolled in the study, HBsAg and anti-HCV were detected in 43 (10.8%; 95% CI: 8.0-14.0%) and 34 (8.5%, 95% CI: 6.0-11.5%) women, respectively. None of the women were co-infected with HBV and HCV. Multivariate analysis showed that circumcision was significantly associated with HBsAg seropositivity (OR = 3.3, 95% CI: 1.1-10.2; p = 0.03), low parity (primigravidae and secundigravidae) and education below secondary level were significantly associated with anti- HCV seropositivity (OR = 3.3, 95% CI: 1.1-10.2; p = 0.03). No other sociodemographic or clinical characteristics (age, residence, history of home delivery, miscarriage, dental manipulation, surgery, and blood transfusion) were significantly associated with HBsAg or anti-HCV seropositivity. CONCLUSION: The results of this study suggest that HBsAg and anti-HCV have high prevalence among pregnant women.
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Authors | Entisar A Murad, Suad M Babiker, Gasim I Gasim, Duria A Rayis, Ishag Adam |
Journal | BMC pregnancy and childbirth
(BMC Pregnancy Childbirth)
Vol. 13
Pg. 127
(Jun 07 2013)
ISSN: 1471-2393 [Electronic] England |
PMID | 23758990
(Publication Type: Journal Article)
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Chemical References |
- Antibodies, Viral
- Hepatitis B Surface Antigens
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Topics |
- Adult
- Antibodies, Viral
(blood)
- Circumcision, Female
- Confidence Intervals
- Cross-Sectional Studies
- Educational Status
- Female
- Hepacivirus
(immunology)
- Hepatitis B
(blood, epidemiology)
- Hepatitis B Surface Antigens
(blood)
- Hepatitis C
(blood, epidemiology)
- Humans
- Multivariate Analysis
- Odds Ratio
- Parity
- Pregnancy
- Pregnancy Complications, Infectious
(blood, epidemiology)
- Prevalence
- Seroepidemiologic Studies
- Yemen
(epidemiology)
- Young Adult
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