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Subcutaneous fat necrosis associated with pancreatitis: histochemical and electron microscopic findings.

Abstract
Subcutaneous fat necrosis associated with pancreatitis has been postulated to be due to the effects of circulating pancreatic lipase. We report positive intracellular staining of adipocytes with a monoclonal antibody to pancreatic lipase in a lesion of subcutaneous pancreatic fat necrosis, and confirm the role of pancreatic lipase in the pathogenesis of this syndrome.
AuthorsS S Dhawan, F Jimenez-Acosta, R J Poppiti Jr, J S Barkin
JournalThe American journal of gastroenterology (Am J Gastroenterol) Vol. 85 Issue 8 Pg. 1025-8 (Aug 1990) ISSN: 0002-9270 [Print] United States
PMID2375312 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Lipase
Topics
  • Adipose Tissue (enzymology, pathology)
  • Humans
  • Immunohistochemistry
  • Lipase (analysis)
  • Male
  • Microscopy, Electron
  • Middle Aged
  • Pancreatitis (complications, enzymology)
  • Panniculitis (complications, enzymology, pathology)

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