Abstract |
Coccidioidomycosis is a fungal infection caused by the Coccidioides species, endemic to the southwestern United States. In healthy people, manifestations range mainly from asymptomatic to mild influenza-like signs, whereas in immunosuppressed patients (eg, transplant recipients) this infection is often a severe disseminated disease. We report a case of primary pulmonary coccidioidomycosis in a 61-year-old man with a renal transplant 7 months earlier. The patient had nonspecific symptoms of pulmonary infection, including weakness, anorexia, and weight loss. Both spherules and endospores of Coccidioides immitis were seen histologically after a transbronchial biopsy of a cavitary lesion. The patient was treated with amphotericin B. At the time of this writing (8 months), he remains disease free.
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Authors | Merih Tepeoglu, Hilal Erinanc, Handan Ozdemir, Hale Turan, Gokhan Moray, Mehmet Haberal |
Journal | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
(Exp Clin Transplant)
Vol. 12
Issue 1
Pg. 71-3
(Feb 2014)
ISSN: 2146-8427 [Electronic] Turkey |
PMID | 23742155
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Antifungal Agents
- Amphotericin B
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Topics |
- Amphotericin B
(therapeutic use)
- Antifungal Agents
(therapeutic use)
- Biopsy
- Coccidioides
(isolation & purification)
- Coccidioidomycosis
(diagnosis, drug therapy, microbiology)
- Humans
- Kidney Transplantation
(adverse effects)
- Lung Diseases, Fungal
(diagnosis, drug therapy, microbiology)
- Male
- Middle Aged
- Time Factors
- Tomography, X-Ray Computed
- Treatment Outcome
- Turkey
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