Aim. To evaluate the efficacy of Brazilian green
propolis in comparison to
miconazole gel in the treatment of Candida-associated
denture stomatitis. Methods. Forty-five
denture stomatitis patients, with palatal mucosa
erythema levels classified according to Newtons's criteria and with positive culture to Candida spp., were randomly divided into three treatment groups: 15 received
miconazole gel 2%, 15 received
propolis gel 2,5%, and 15 received
propolis 24% for mouthwash. After four daily use lasting two weeks, they were reexamined for the
denture stomatitis degree and for a second culture of Candida. The Wilcoxon's test was applied to compare the results of clinical classification of the
denture stomatitis and the Candida spp. colonies numbers, before and after each treatment. The Kruskall-Wallis's test was used to compare efficacy among the three treatment groups. Results. There were a significant reduction or complete remission of
denture stomatitis (P < 0.05) and a significant decrease of Candida colonies for the three groups (P < 0.05). There was no difference in the efficacy among the treatment groups (P > 0.05). Conclusion. Brazilian green
propolis has a similar effect as
miconazole in the treatment of Candida-associated
denture stomatitis being an alternative in the
therapeutics of this condition.