Abstract | BACKGROUND: AIMS AND OBJECTIVES: To evaluate the serum GGT levels in patients with chronic anicteric non alcoholic liver diseases and to show that it can be used as a noninvasive diagnostic biomarker for the diagnosis of chronic anicteric non alcoholic liver disorders. MATERIALS AND METHODS: This was a case control study, in which 50 cases and 50 controls were selected.The liver function tests with a special reference to the serum level of GGT were measured in the laboratory for both the cases and the controls and the serum GGT levels of the cases were compared with those of the controls. The Chi-square and the Fisher exact tests were used to find the significance of the proportions of the study parameters between the cases and the controls. The Student's t test (two tailed) was used to find the significance mean pattern of the study parameters between the cases and the controls. RESULTS: The mean serum GGT level was 38.73±11 IU/L in the cases and in the controls, it was 20.42±9 IU/L(p<0.001).The mean value of serum ALT was 41.37±12.5 vs 16.3±8iu/l(p<0.001), that of AST was 28.14±8 vs 17.56±8.5iu/l(p<0.05), that of total bilirubin was 0.9±0.3 vs 0.5±0.2mg/dl and that of serum albumin was 4.17±0.6 vs 4.5±0.75gm/dl, as were seen in the cases and the controls respectively. CONCLUSION:
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Authors | Krishnamurthy H A |
Journal | Journal of clinical and diagnostic research : JCDR
(J Clin Diagn Res)
Vol. 7
Issue 4
Pg. 691-4
(Apr 2013)
ISSN: 2249-782X [Print] India |
PMID | 23730648
(Publication Type: Journal Article)
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