Abstract | OBJECTIVES: STUDY DESIGN: A Pubmed and Embase search was performed with the focus on treatment and treatment duration for cervicofacial actinomycosis. The hospital records of all patients presenting to our department with head and neck infection from January 2000 to December 2010 were reviewed, retrospectively. The following data were collected: age, gender, clinical presentation, aetiology, duration of symptoms, microbiological findings, treatment, and duration of treatment. The treatment and treatment duration is subsequently compared to the literature. RESULTS: The literature search provided 12 studies meeting the inclusion criteria. All studies were retrospective in nature. Penicillin or amoxicillin/clavulanic acid are the preferred antibiotic regimens found in the literature. Most of our patients were treated with a combination of penicillin G 12 million units/day and metronidazol 500 mg 3/day, most commonly for a duration of 1 - 4 weeks, being shorter than the 3 - 52 weeks reported in the literature. CONCLUSION: When actinomycosis is suspected, our review has shown that a surgical approach in combination with intravenous penicillin and metronidazol until clinical improvement is seen, followed by oral antibiotics for 2 - 4 weeks is generally efficient.
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Authors | Meshkan Moghimi, Erik Salentijn, Yvette Debets-Ossenkop, K H Karagozoglu, Tymour Forouzanfar |
Journal | Medicina oral, patologia oral y cirugia bucal
(Med Oral Patol Oral Cir Bucal)
Vol. 18
Issue 4
Pg. e627-32
(Jul 01 2013)
ISSN: 1698-6946 [Electronic] Spain |
PMID | 23722146
(Publication Type: Journal Article, Review)
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Chemical References |
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Topics |
- Actinomycosis, Cervicofacial
(surgery, therapy)
- Anti-Bacterial Agents
(therapeutic use)
- Combined Modality Therapy
- Humans
- Retrospective Studies
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