Parry-Romberg syndrome vasculopathy and its treatment with botulinum toxin.

Abstract

Parry-Romberg syndrome is a rare condition characterized by progressive, hemifacial atrophy, hair loss, enophthalmos, retinal vasculopathy occasionally associated with hemicranial pain syndrome (secondary trigeminal neuralgia). The cause of the condition is unknown; however, substantial evidence suggests that vasculopathy plays a significant role in the genesis of the neurologic damage and facial lipodystrophy. Herein describes a case of Parry-Romberg syndrome treated with repetitive botulinum type A toxin injections, with almost complete resolution of severe chronic pain.

• Authors: Gary E Borodic, Paul Caruso, Martin Acquadro, Sarah Chick
• Journal: Ophthalmic plastic and reconstructive surgery (Ophthalmic Plast Reconstr Surg) 2014 Jan-Feb Vol. 30 Issue 1 Pg. e22-5 ISSN: 1537-2677 [Electronic] United States
• PMID: 23719195 (Publication Type: Case Reports, Journal Article)

Chemical References

• Neuromuscular Agents
• Technetium
• Botulinum Toxins, Type A

Topics

• Botulinum Toxins, Type A (therapeutic use)
• Facial Hemiatrophy (diagnosis, drug therapy)
• Female
• Humans
• Injections, Intradermal
• Magnetic Resonance Imaging
• Middle Aged
• Neuromuscular Agents (therapeutic use)
• Technetium
• Tomography, Emission-Computed, Single-Photon
• Tomography, X-Ray Computed