[Fibrinogen-thrombin as bridge therapy in massive hemoptysis].

Abstract

This article presents the case of a young woman with massive hemoptysis (1,000 mL in 6 hours) due to tuberculosis, which could not be controlled by insertion of a Fogarty catheter through a fiber-optic bronchoscope. Because of asphyxia and persistent bleeding risk we instilled fibrinogen-thrombin through a fiber-optic bronchoscope inserted catheter, achieving bleeding cessation and permitting the placing of a double-lumen oro-tracheal tube. Later on, the patient underwent lobectomy and anti-tuberculosis treatment. The fibrinogen-thrombin could be considered as a bridge, transitory measure for massive hemoptysis, while definitive treatment could be established.

• Authors: Francisco Cuervo, Luis F Giraldo, Carlos Vélez, María R Forero
• Journal: Biomedica : revista del Instituto Nacional de Salud (Biomedica) 2013 Jan-Mar Vol. 33 Issue 1 Pg. 28-30 ISSN: 2590-7379 [Electronic] Colombia
• Vernacular Title: Fibrinógeno-trombina como tratamiento puente en un caso de hemoptisis masiva.
• PMID: 23715303 (Publication Type: Case Reports, English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antitubercular Agents
• Drug Combinations
• Fibrin Tissue Adhesive
• beriplast P combi set
• Fibrinogen
• Factor XIII
• Aprotinin
• Thrombin

Topics

• Adult
• Antitubercular Agents (therapeutic use)
• Aprotinin (administration & dosage, therapeutic use)
• Balloon Occlusion
• Bronchoscopy (methods)
• Catheters
• Cholangiopancreatography, Endoscopic Retrograde (instrumentation)
• Combined Modality Therapy
• Drug Combinations
• Emergencies
• Factor XIII (administration & dosage, therapeutic use)
• Female
• Fiber Optic Technology
• Fibrin Tissue Adhesive (administration & dosage, therapeutic use)
• Fibrinogen (administration & dosage, therapeutic use)
• Hemoptysis (etiology, surgery, therapy)
• Hemostatic Techniques (instrumentation)
• Humans
• Intubation, Intratracheal (instrumentation)
• Pneumonectomy
• Thrombin (administration & dosage, therapeutic use)
• Tuberculosis, Pulmonary (complications, drug therapy, surgery)