Abstract | INTRODUCTION: Prevalence of multiple primary malignancies is slowly increasing due to prolonged survival of cancer patients with advances in diagnostic and therapeutic modalities. The reasons may be environmental modifications, genetic predisposition or therapy induced. We describe a case of a 64-year-old woman with three different metachronous primary malignancies managed at our center since 4 years. PRESENTATION OF CASE: DISCUSSION: In present case patient did not have significant risk factors for development of carcinoma of small intestine, breast and ovary. Our patient underwent surgical excision three times and received total 16 chemotherapy cycles of different regimens during management of all three primary malignancies. Development of second and higher order primary malignancy after successful management of previous one should be always kept in mind. CONCLUSION: Awareness, suspicion of multiple primary malignancy and aggressive diagnostic work up plays crucial role in their detection at earlier stage for better outcome. In addition choice of appropriate chemotherapeutic agents and their regimens remains the cornerstone while managing the patients with multiple primary malignancies.
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Authors | Unmesh Takalkar, Balaji N Asegaonkar, Pushpa Kodlikeri, Shilpa Asegaonkar, Brijmohan Sharma, Suresh H Advani |
Journal | International journal of surgery case reports
(Int J Surg Case Rep)
Vol. 4
Issue 7
Pg. 593-6
( 2013)
ISSN: 2210-2612 [Print] Netherlands |
PMID | 23702365
(Publication Type: Journal Article)
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Copyright | Copyright © 2013 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved. |