Abstract |
Patients with chronic headache and medication overuse are particularly difficult to treat, with no one approach being universally accepted. Some type of withdrawal program, however, is typically implemented before beginning a pharmacological prophylaxis treatment. Different withdrawal modalities have been performed for managing these patients: at first step, in-patient withdrawal has been confirmed effective in preceding clinical experiences. In recent years, new modalities for withdrawal have been developed as day-hospital setting. Purpose of this study was to determine the clinical course of a sample of chronic migraine patients with medication overuse 3 years after day-hospital withdrawal. A group of 202 patients were treated. Patients were suffering from chronic migraine with medication overuse according with IHS criteria. All patients were submitted to a day-hospital withdrawal and then they were followed with meetings every 3 months until the first year and then every 6 months until the last follow-up 3 years after withdrawal. Eighty patients achieved the last follow-up meeting 3 years after withdrawal. Patients clinically improved, significantly, both for days of headache per month and consumption of medications per month. From these results, the day-hospital setting for withdrawal, followed by periodic clinical meetings, seems to be effective for this category of patients to improve significantly at long-term headache frequency and analgesics intake.
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Authors | L Grazzi, F Andrasik, S Usai, G Bussone |
Journal | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
(Neurol Sci)
Vol. 34 Suppl 1
Pg. S167-9
(May 2013)
ISSN: 1590-3478 [Electronic] Italy |
PMID | 23695072
(Publication Type: Clinical Trial, Journal Article)
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Chemical References |
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Topics |
- Analgesics
(adverse effects)
- Chronic Disease
(drug therapy)
- Day Care, Medical
(methods)
- Follow-Up Studies
- Humans
- Migraine Disorders
(chemically induced, drug therapy)
- Substance Withdrawal Syndrome
- Substance-Related Disorders
(therapy)
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