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Successful switch to oral therapy with doxycycline in the case of an actinomycotic hepatic abscess.

Abstract
A 72-year-old female was admitted with the symptoms of malaise, loss of appetite, upper right quadrant pain, fever, and sweats, which had been present for last 7 days. CT-scan of the abdomen revealed a hypodense mass in the right liver lobe; histopathological examination of the biopsy specimen yielded a diagnosis of actinomycotic abscess. Treatment with intravenous ampicillin for 8 weeks followed by a course of oral doxicycline for 28 weeks resulted in the complete resolution of the abscess.
AuthorsDiana Petrache, Gabriel-Adrian Popescu
JournalJournal of infection in developing countries (J Infect Dev Ctries) Vol. 7 Issue 5 Pg. 421-3 (May 13 2013) ISSN: 1972-2680 [Electronic] Italy
PMID23669433 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Ampicillin
  • Doxycycline
Topics
  • Actinomycosis (drug therapy, microbiology, pathology)
  • Administration, Intravenous
  • Administration, Oral
  • Aged
  • Ampicillin (administration & dosage)
  • Anti-Bacterial Agents (administration & dosage)
  • Biopsy
  • Doxycycline (administration & dosage)
  • Female
  • Histocytochemistry
  • Humans
  • Liver (pathology)
  • Liver Abscess (drug therapy, microbiology, pathology)
  • Microscopy
  • Radiography, Abdominal
  • Tomography, X-Ray Computed
  • Treatment Outcome

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