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Autologous fat grafting for treatment of facial atrophy in Behcet's disease: a case report.

Abstract
Behcet's disease (BD) is an autoimmune & autoinflammatory disease of unclear etiology characterized by recurrent oral & genital ulcers as well as other systemic manifestations. A key pathogenesis is excessive inflammatory wound healing response. While descriptions of the cutaneous manifestations of disease are limited to short-term consequences such as extensive pustule and papule formation in response to minor tissue injury, the long-term consequences are significant fibrosis and scarring of epithelial tissue. We describe the case of a patient with Behcet's disease who presented with unilateral facial atrophy secondary to minor trauma to the oral mucosa. She was treated with autologous fat grafting. Though a rare disease, plastic surgeons should be aware of the entity of Behcet's disease and its complications of tissue atrophy that may require reconstructive surgery.
AuthorsZ-Hye Lee, Kamran Khoobehi, Ernest S Chiu
JournalJournal of plastic, reconstructive & aesthetic surgery : JPRAS (J Plast Reconstr Aesthet Surg) Vol. 66 Issue 12 Pg. 1759-62 (Dec 2013) ISSN: 1878-0539 [Electronic] Netherlands
PMID23642794 (Publication Type: Case Reports, Journal Article)
CopyrightCopyright © 2013 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
Topics
  • Adipose Tissue (transplantation)
  • Atrophy
  • Autografts
  • Behcet Syndrome (complications, pathology, surgery)
  • Cheek (pathology)
  • Cicatrix (surgery)
  • Facial Asymmetry (etiology, pathology, surgery)
  • Female
  • Humans
  • Injections, Subcutaneous
  • Middle Aged
  • Oral Ulcer (pathology)
  • Plastic Surgery Procedures

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