Abstract | OBJECTIVE: METHODS: Adult male Sprague-Dawley rats were divided into three groups : the control group, the 10 minutes after recovery from isoflurane anesthesia group, and the 2 hours after recovery from isoflurane anesthesia group (n=8 in each group). The rats in the isoflurane-exposed groups were anesthetized with 1.2% isoflurane in 75% nitrous oxide and 25% oxygen for 2 hours in a Plexiglas anesthetizing chamber. Short-term memory was determined using the step-down avoidance task. BDNF and TrkB expressions in the hippocampus were evaluated by immunofluorescence staining and western blot analysis. RESULTS: CONCLUSION:
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Authors | Han-Jin Cho, Yun-Hee Sung, Seung-Hwan Lee, Jun-Young Chung, Jong-Man Kang, Jae-Woo Yi |
Journal | Journal of Korean Neurosurgical Society
(J Korean Neurosurg Soc)
Vol. 53
Issue 3
Pg. 139-44
(Mar 2013)
ISSN: 2005-3711 [Print] Korea (South) |
PMID | 23634262
(Publication Type: Journal Article)
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