Multiple cutaneous and uterine leiomyomatosis syndrome: a review.

Abstract

Multiple cutaneous and uterine leiomyomatosis is an autosomal dominant disease characterized by leiomyomas of the skin and uterus. A small proportion of patients affected by multiple cutaneous and uterine leiomyomatosis will develop renal cell carcinoma and this condition is known as hereditary leiomyomatosis and renal cell carcinoma. Diagnosis usually occurs during histological analysis of a cutaneous biopsy. Management should involve a multidisciplinary team along with periodical radiological studies to closely monitor tumor size in the uterus and kidneys. Gonadotropin-releasing hormone analogues are helpful in reducing the size of uterine fibroids.

• Authors: Sonal Choudhary, Michael McLeod, Daniele Torchia, Paolo Romanelli
• Journal: The Journal of clinical and aesthetic dermatology (J Clin Aesthet Dermatol) Vol. 6 Issue 4 Pg. 16-21 (Apr 2013) ISSN: 1941-2789 [Print] United States
• PMID: 23630637 (Publication Type: Journal Article)