Abstract | BACKGROUND: The purpose of this cross-sectional study was to test the hypothesis that serum vitamin D levels are abnormally low in sleep clinic patients admitting to chronic nonspecific musculoskeletal pain and to assess the associated risk factors. A secondary purpose was to identify a clinical biomarker for vitamin D deficiency. METHODS: We enrolled 153 consecutive patients who admitted to the presence of chronic nonspecific musculoskeletal pain during a comprehensive sleep evaluation at a specialist sleep medicine clinic within an academic center. Venous blood sampling was performed for determination of serum 25-hydroxyvitamin D. Risk factors for vitamin D deficiency (25-hydroxyvitamin D < 20 ng/mL) were identified by odds ratios. Receiver-operating characteristic curve analysis was performed with 10-fold cross-validation to identify a biomarker for vitamin D deficiency calculated by linear discriminant analysis. RESULTS: CONCLUSION:
|
Authors | David E McCarty, Aronkumar Reddy, Quinton Keigley, Paul Y Kim, Stephen Cohen, Andrew A Marino |
Journal | Nature and science of sleep
(Nat Sci Sleep)
Vol. 5
Pg. 37-42
( 2013)
ISSN: 1179-1608 [Print] New Zealand |
PMID | 23620692
(Publication Type: Journal Article)
|