Phenytoin-induced gingival enlargement: a dental awakening for patients with epilepsy.

Abstract

Drug-induced gingival enlargement is the term now used to describe medication-related gingival hypertrophy or hyperplasia, a condition commonly induced by three main classes of drugs: anticonvulsants, antihypertensive calcium channel blockers and the immunosuppressant cyclosporine. The pathogenesis of drug-induced gingival enlargement is uncertain and there appears to be no unifying hypothesis that links together the three commonly implicated drugs. Phenytoin-induced gingival overgrowth is a well known and frequently reported gingival lesion, which was first detected in 1939. This case report consists of phenytoin usage, duration and poor oral hygiene.

• Authors: Ravi Prakah Sasankoti Mohan, Khushboo Rastogi, Rajarshi Bhushan, Sankalp Verma
• Journal: BMJ case reports (BMJ Case Rep) Vol. 2013 (Apr 23 2013) ISSN: 1757-790X [Electronic] England
• PMID: 23616318 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anticonvulsants
• Phenytoin

Topics

• Adult
• Anticonvulsants (adverse effects)
• Epilepsy (drug therapy)
• Gingival Hyperplasia (chemically induced)
• Humans
• Male
• Phenytoin (adverse effects)