Potential anti-inflammatory effect of low-level laser therapy on the experimental reflux laryngitis: a preliminary study.
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| Abstract |
The most common cause of laryngitis is the laryngopharyngeal reflux disease. The symptoms of laryngitis can be hoarseness, globus, chronic cough, voice fatigue, throat pain, and dysphagia. Low-level laser therapy (LLLT) is beneficial to reduce the pain and inflammatory response without side effects. Therefore, LLLT may be a useful tool for the treatment of laryngitis. This study proposes to analyze the effect of laser therapy in a model of reflux-induced laryngitis. The animals were randomly put into three groups: control--non-intubated; nasogastric intubation--intubated; and nasogastric intubation with laser therapy-intubated treated with 105-J/cm(2) laser irradiation. For the induction of laryngitis, the animals were anesthetized and a nasogastric tube was inserted through the nasopharynx until it reached the stomach, for 1 week. Thereafter, measurement of myeloperoxidase activity and the histopathological procedures were performed. In conclusion, we observed in this study that 105-J/cm(2) infrared laser reduced the influx of neutrophils in rats, and it improved the reparative collagenization of the laryngeal tissues.
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| Authors | Renata R Marinho, Renata M Matos, Jandson S Santos, Maria A G Ribeiro, Ronaldo A Ribeiro, Roberto C P Lima Jr, Ricardo L C Albuquerque Jr, Sara M Thomazzi |
| Journal | Lasers in medical science (Lasers Med Sci) Vol. 29 Issue 1 Pg. 239-43 (Jan 2014) ISSN: 1435-604X [Electronic] England |
| PMID | 23613090 (Publication Type: Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't) |
| Chemical References |
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