New profiles of posterior pole retinal thickness map in healthy Korean eyes measured by spectral-domain optical coherence tomography.

Abstract

PURPOSE:

To analyze posterior pole retinal thickness using the new Spectralis HRA + OCT protocol and compare two commercially available spectral-domain optical coherence tomography instruments (Spectralis HRA + OCT and Cirrus HD-OCT) in young healthy eyes.

METHODS:

Retinal thickness in 178 young healthy eyes was measured using the volume scan mode and Posterior Pole Asymmetry Analysis of the Spectralis HRA + OCT and the macular cube 512 × 128 protocol of the Cirrus HD-OCT. Topologic differences in posterior pole retinal thickness between the two spectral-domain optical coherence tomographies were compared, and the relationship between retinal thickness and age or refractive error/axial length was assessed.

RESULTS:

Mean retinal thickness measurements in all 9 Early Treatment Diabetic Retinopathy Study Report areas were significantly greater with the Spectralis HRA + OCT than with the Cirrus HD-OCT (P < 0.001). Retinal thickness measured with the new Spectralis HRA + OCT protocol positively correlated with refractive error (P < 0.05) and negatively correlated with axial length (P < 0.05), mainly in the temporal areas. As axial length increased and refractive error decreased, retinal thickness decreased significantly at the outer temporal areas compared with the nasal areas (P < 0.05). Foveal thickness measured with the Spectralis HRA + OCT correlated significantly with refractive error (r = -0.151; P = 0.022) and axial length (r = 0.352; P < 0.001).

CONCLUSION:

Posterior pole retinal thickness measurements in young healthy eyes should provide more detailed standard values for diagnosing and managing retinal disease.

• Authors: Kook Young Kim, Hyung Woo Kwak, Moosang Kim, Young Gyun Kim, Seung-Young Yu
• Journal: Retina (Philadelphia, Pa.) (Retina) 2013 Nov-Dec Vol. 33 Issue 10 Pg. 2139-48 ISSN: 1539-2864 [Electronic] United States
• PMID: 23609125 (Publication Type: Journal Article)

Topics

• Adult
• Asian People
• Female
• Humans
• Intraocular Pressure (physiology)
• Male
• Ophthalmoscopy
• Organ Size
• Posterior Eye Segment (anatomy & histology)
• Prospective Studies
• Reference Values
• Republic of Korea
• Retina (anatomy & histology)
• Tomography, Optical Coherence
• Visual Acuity (physiology)
• Young Adult