Simplified methods of topical fluoride administration: effects in individuals with hyposalivation.

Abstract

The aim was to compare fluoride (F) levels in individuals with normal salivary secretion and hyposalivation in connection with their use of F solutions and toothpaste. Seven individuals with normal salivation and nine with hyposalivation rinsed with 0.2% NaF solution for 1 minute. In addition, individuals with hyposalivation performed the following: (i) 0.2% NaF rinsing for 20 seconds, (ii) rubbing oral mucosa with a swab soaked with 0.2% NaF solution, and (iii) brushing with 5,000 ppm F (1.1% NaF) toothpaste. Subjects characterized by hyposalivation reached approximately five times higher peak values of F concentrations in saliva after 1 minute rinsing with the F solution and higher area under the curve (AUC) values. The simplified methods exhibited the same AUC values as did 1 minute of rinsing. Brushing with 5,000 ppm F toothpaste resulted in higher AUC values than did the simplified methods. The F concentrations reached higher levels in individuals with hyposalivation compared to those with normal salivation. The simplified methods tested showed similar effects as conventional methods.

• Authors: Pia Gabre, Ulla Moberg Sköld, Dowen Birkhed
• Journal: Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry (Spec Care Dentist) 2013 May-Jun Vol. 33 Issue 3 Pg. 111-7 ISSN: 1754-4505 [Electronic] United States
• PMID: 23600981 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: ©2012 Special Care Dentistry Association and Wiley Periodicals, Inc.

Chemical References

• Cariostatic Agents
• Fluorides, Topical
• Mouthwashes
• Toothpastes
• Sodium Fluoride

Topics

• Administration, Buccal
• Administration, Topical
• Aged
• Aged, 80 and over
• Area Under Curve
• Cariostatic Agents (administration & dosage)
• Case-Control Studies
• Fluorides, Topical (administration & dosage)
• Humans
• Middle Aged
• Mouthwashes (administration & dosage, chemistry)
• Saliva (chemistry, metabolism)
• Secretory Rate
• Sodium Fluoride (administration & dosage)
• Statistics, Nonparametric
• Time Factors
• Toothbrushing
• Toothpastes (administration & dosage, chemistry)
• Xerostomia (physiopathology)