A rare occurrence and management of familial schwannomatosis.

Abstract

We are presenting a familial schwannomatosis without the features of neurofibromatosis (NF). We retrospectively reviewed the hospital charts, radiology films, operative notes and pathology slides of the patient. There was a family history of schwannomatosis. The patient had contrast-enhanced MRI, which was negative for vestibular schwannomas. The patient underwent surgical excision of symptomatic lesions. Histopathology confirmed these lesions as schwannomas consisting of areas of Antoni A and B, and immunohistochemical study was positive for S-100 protein. We recommend surgery for symptomatic lesions. Asymptomatic tumours can be monitored. Regular follow-up is essential as they may develop fresh lesions at any time. The relevant literature is discussed.

• Authors: Ramesh G Reddy, Vanaja Reddy Banda, Shankar Gunadal, Naveen Reddy Banda
• Journal: BMJ case reports (BMJ Case Rep) Vol. 2013 (Apr 16 2013) ISSN: 1757-790X [Electronic] England
• PMID: 23595180 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Biopsy
• Humans
• Magnetic Resonance Imaging
• Male
• Neurilemmoma (genetics, pathology, surgery)
• Neurofibromatoses (genetics, pathology, surgery)
• Skin Neoplasms (genetics, pathology, surgery)
• Young Adult