Abstract | INTRODUCTION: METHODS: RESULTS: CONCLUSIONS: These results show that muraglitazar has anti-inflammatory properties both in vitro and in vivo and these effects reflect the agonistic action through both PPARα and PPARγ.
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Authors | Erja-Leena Paukkeri, Tiina Leppänen, Mira Lindholm, Mun Fei Yam, Mohd Zaini Asmawi, Anne Kolmonen, Paula H Aulaskari, Eeva Moilanen |
Journal | Arthritis research & therapy
(Arthritis Res Ther)
Vol. 15
Issue 2
Pg. R51
(Apr 17 2013)
ISSN: 1478-6362 [Electronic] England |
PMID | 23594962
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Anti-Inflammatory Agents
- Oxazoles
- PPAR alpha
- PPAR gamma
- Glycine
- muraglitazar
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Topics |
- Animals
- Anti-Inflammatory Agents
(pharmacology)
- Blotting, Western
- Enzyme-Linked Immunosorbent Assay
- Gene Expression
(drug effects)
- Glycine
(analogs & derivatives, pharmacology)
- HEK293 Cells
- Humans
- In Vitro Techniques
- Inflammation
(immunology)
- Macrophages
(drug effects, immunology)
- Mice
- Oxazoles
(pharmacology)
- PPAR alpha
(agonists)
- PPAR gamma
(agonists)
- Real-Time Polymerase Chain Reaction
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