Isolated bilateral ptosis as an early sign of guillain-barré syndrome.

Abstract

Background. Guillain-Barré syndrome (GBS) has many variants with distinct presentations. Ptosis as an initial presentation is rare. Case Report. We describe a young female with bilateral ptosis without ophthalmoplegia as the initial presentation of Guillain-Barré ptosis in an anti-GQ1b IgG antibody negative patient with a favorable outcome to intravenous immunoglobulins. Objectives. Our paper highlights the importance of recognizing GBS as a potential etiology in a patient presenting with isolated ptosis, particularly since the course of GBS can be more dramatic than in the anti-GBQ1b syndromes such as ophthalmoparesis without ataxia and Miller Fisher syndrome or ocular myasthenia. Conclusion. This is the first paper of anti-GBQ1b antibody negative GBS presenting with isolated ptosis without ophthalmoparesis. GBS should be included in the list of differential diagnosis of such presentations.

• Authors: Yahia Z Imam, Dirk Deleu
• Journal: Case reports in neurological medicine (Case Rep Neurol Med) Vol. 2013 Pg. 178291 ( 2013) ISSN: 2090-6668 [Print] United States
• PMID: 23585975 (Publication Type: Journal Article)