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In vivo acquired daptomycin resistance during treatment of methicillin-resistant Staphylococcus aureus endocarditis.

Abstract
This clinical case reports the emergence of a daptomycin-resistant Staphylococcus aureus isolate during daptomycin treatment in a patient with right-sided infective endocarditis who had never been treated with vancomycin.
AuthorsLaurent Dortet, Nadia Anguel, Nicolas Fortineau, Christian Richard, Patrice Nordmann
JournalInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases (Int J Infect Dis) Vol. 17 Issue 11 Pg. e1076-7 (Nov 2013) ISSN: 1878-3511 [Electronic] Canada
PMID23578850 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
CopyrightCopyright © 2013 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
Chemical References
  • Anti-Bacterial Agents
  • Daptomycin
Topics
  • Anti-Bacterial Agents (pharmacology, therapeutic use)
  • Daptomycin (pharmacology, therapeutic use)
  • Drug Resistance, Multiple, Bacterial
  • Endocarditis, Bacterial (diagnosis, drug therapy)
  • Female
  • Humans
  • Methicillin-Resistant Staphylococcus aureus (drug effects)
  • Microbial Sensitivity Tests
  • Middle Aged
  • Staphylococcal Infections (diagnosis, drug therapy)

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