Abstract | BACKGROUND: METHODS: We analyzed nine patients who required ventilator care due to ALI after pneumonectomy. Five of these patients underwent conventional ventilator care (group I), and four patients underwent ventilator care and were administrated NEI (group II). We retrospectively analyzed the lung injury score (LIS) for 10 days after intubation. RESULTS: The LIS before intubation satisfied the diagnostic criteria of ALI or acute respiratory distress syndrome (ARDS) in all patients. After intubation, the LIS improved in both groups. But, as times went on, the mean value of the LIS in group II was lower compared to group I. In group I, only one patient underwent extubation. In group II, extubation was possible in three patients. Mortality rates were 80% in group I and 25% in group II. CONCLUSIONS:
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Authors | Sang Kwon Lee, Bong Soo Son, Jung Joo Hwang, Kil Dong Kim, Do Hyung Kim |
Journal | Journal of cardiothoracic surgery
(J Cardiothorac Surg)
Vol. 8
Pg. 69
(Apr 08 2013)
ISSN: 1749-8090 [Electronic] England |
PMID | 23566653
(Publication Type: Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Proteinase Inhibitory Proteins, Secretory
- Sulfonamides
- sivelestat
- Glycine
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Topics |
- Acute Lung Injury
(drug therapy, etiology, mortality, therapy)
- Adult
- Aged
- Combined Modality Therapy
- Drug Administration Schedule
- Glycine
(analogs & derivatives, therapeutic use)
- Humans
- Infusions, Intravenous
- Male
- Middle Aged
- Pneumonectomy
- Postoperative Complications
(drug therapy, mortality, therapy)
- Proteinase Inhibitory Proteins, Secretory
(therapeutic use)
- Respiration, Artificial
- Respiratory Distress Syndrome
(drug therapy, etiology, mortality, therapy)
- Retrospective Studies
- Sulfonamides
(therapeutic use)
- Treatment Outcome
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