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Creep and fatigue behavior of a novel 2-component paste-like formulation of acrylic bone cements.

Abstract
The fatigue and creep performance of two novel acrylic bone cement formulations (one bone cement without antibiotics, one with antibiotics) was compared to the performance of clinically used bone cements (Osteopal V, Palacos R, Simplex P, SmartSet GHV, Palacos R+G and CMW1 with Gentamicin). The preparation of the novel bone cement formulations involves the mixing of two paste-like substances in a static mixer integrated into the cartridge which is used to apply the bone cement. The fatigue performance of the two novel bone cement formulations is comparable to the performance of the reference bone cements. The creep compliance of the bone cements is significantly influenced by the effects of physical ageing. The model parameters of Struik's creep law are used to compare the creep behavior of different bone cements. The novel 2-component paste-like bone cement formulations are in the group of bone cements which exhibit a higher creep resistance.
AuthorsUlrike Köster, Raimund Jaeger, Mareike Bardts, Christian Wahnes, Hubert Büchner, Klaus-Dieter Kühn, Sebastian Vogt
JournalJournal of materials science. Materials in medicine (J Mater Sci Mater Med) Vol. 24 Issue 6 Pg. 1395-406 (Jun 2013) ISSN: 1573-4838 [Electronic] United States
PMID23563979 (Publication Type: Comparative Study, Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Ointments
  • Polymethyl Methacrylate
Topics
  • Drug Compounding (methods)
  • Elastic Modulus
  • Hardness
  • Materials Testing
  • Ointments (chemistry)
  • Polymethyl Methacrylate (chemistry)
  • Tensile Strength
  • Viscosity

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