Severe infections caused by Panton-Valentine leukocidin-positive Staphylococcus aureus in infants: report of three cases and review of literature.

Abstract

UNLABELLED:

We report three cases of severe infections in infants caused by Panton-Valentine leukocidin positive Staphylococcus aureus and evolved with a positive outcome. The literature of Panton-Valentine leukocidin positive Staphylococcus aureus infections in infants is reviewed.

CONCLUSION:

Our findings suggest that a prompt identification of Panton-Valentine leukocidin positive Staphylococcus aureus and an appropriate therapy can reduce mortality and long-term sequelae. Further research is needed to specify features of Panton-Valentine leukocidin positive Staphylococcus aureus infections in infants.

• Authors: Carlotta Montagnani, Priscilla Cocchi, Leila Bianchi, Massimo Resti, Maurizio de Martino, Luisa Galli
• Journal: Acta paediatrica (Oslo, Norway : 1992) (Acta Paediatr) Vol. 102 Issue 6 Pg. e284-7 (Jun 2013) ISSN: 1651-2227 [Electronic] Norway
• PMID: 23551699 (Publication Type: Case Reports, Journal Article, Review)
• Copyright: ©2013 The Author(s)/Acta Paediatrica ©2013 Foundation Acta Paediatrica.

Chemical References

• Acetamides
• Anti-Infective Agents
• Bacterial Toxins
• Exotoxins
• Leukocidins
• Oxazolidinones
• Panton-Valentine leukocidin
• Linezolid

Topics

• Acetamides (administration & dosage)
• Anti-Infective Agents (administration & dosage)
• Bacterial Toxins (metabolism)
• Exotoxins (metabolism)
• Female
• Humans
• Infant
• Leukocidins (metabolism)
• Linezolid
• Male
• Oxazolidinones (administration & dosage)
• Respiratory Insufficiency (microbiology)
• Retropharyngeal Abscess (microbiology)
• Staphylococcal Infections (metabolism, microbiology, surgery)
• Staphylococcus aureus (metabolism)
• Tomography, X-Ray Computed