Abstract | OBJECTIVE: METHODS: In this retrospective study, patients with cholestasis admitted to the pediatric gastroenterology ward in a referral hospital in Shiraz from January 2006 to January 2010 and underwent liver biopsy were evaluated. Clinical and paraclinical status of children with the pathologic diagnosis of PIBD was assessed. FINDINGS: Disease was presented in all jaundiced patients with aged in average 3 days at presentation. Seven patients had the criteria of AGS. Despite medical treatment, cholestasis was not controlled in 6 (28.6%) patients. Liver transplantation led to the survival of 5 patients while the other patient who did not undergo liver transplantation died at 2 months of age. One patient underwent peritoneal dialysis due to renal insufficiency and died at 9 months of age. After 1-5 years of follow-up, the mortality rate was 9.5%. CONCLUSION:
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Authors | Zahmatkeshan Mozhgan, Geramizadeh Bita, Haghighat Mahmood, Enteshari Hajar |
Journal | Iranian journal of pediatrics
(Iran J Pediatr)
Vol. 23
Issue 1
Pg. 65-70
(Feb 2013)
ISSN: 2008-2142 [Print] Netherlands |
PMID | 23550220
(Publication Type: Journal Article)
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