Endometriosis - clinical approach based on histological findings.

Abstract

Endometriosis is a benign disease defined by the presence of endometrial glands and stroma outside of the uterus and is associated with both pelvic pain and infertility. The most common sites of endometriosis, in decreasing order of frequency, are the ovaries, anterior and posterior cul-de-sac, posterior broad ligaments, uterosacral ligaments, uterus, fallopian tubes, sigmoid colon, appendix, and round ligaments. The main treatment is surgical, but often-microscopic islands of endometrial tissue remain, which proliferate and are responsible for relapses. We tested the efficacy of two drugs (Medroxyprogesterone and Triptorelinum), administered for six months to prevent recurrence after surgery. Treatment with Medroxyprogesterone was 100% effective in terms of relapse, while Triptorelinum could not prevent recurrence of endometriosis.

• Authors: C Cristescu, Andreea Velişcu, B Marinescu, Anca Pătraşcu, E T Traşcă, O T Pop
• Journal: Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie (Rom J Morphol Embryol) Vol. 54 Issue 1 Pg. 91-7 ( 2013) ISSN: 2066-8279 [Electronic] Romania
• PMID: 23529314 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Adolescent
• Adult
• Endometriosis (drug therapy, pathology, surgery)
• Female
• Humans
• Middle Aged
• Young Adult