To study the postnatal growth of very low birth weight infant (VLBWI) and its relevant influencing factors during hospitalization.
METHOD: (1) The incidence of IUGR at birth was 34.4%, while the incidence of EUGR on discharge was 72.1%. The mean daily growth rate to
body weight of IUGR group was higher than that of non-IUGR group [(12.5 ± 2.7) g/kg vs (11.3 ± 2.5) g/kg, P = 0.002]. The increasing incidence from IUGR to EUGR, IUGR group was higher than non-IUGR group (96.8% vs 59.2%, P = 0.000). (2) The mean daily energy and
protein intake in postnatal time of 1 week [62 (51, 69) kcal/kg vs 56 (45, 64) kcal/kg (1 kcal = 4.1840 kJ), 1.7 (1.3, 2.0) g/kg vs 1.6 (1.2, 1.8) g/kg], 2 weeks [83 (71, 94) kcal/kg vs 76 (66, 88) kcal/kg, 2.6 (2.1, 2.9) g/kg vs 2.3 (1.9, 2.7) g/kg], 4 weeks [107 (94, 120) kcal/kg vs 95 (85, 108) kcal/kg, 3.3 (2.7, 3.6) g/kg vs 2.7 (2.4, 3.2) g/kg], before total
enteral nutrition [103 (96, 110) kcal/kg vs 97 (89, 106) kcal/kg, 3.1 (2.6, 3.4) g/kg vs 2.8 (2.4, 3.3) g/kg] and the whole hospitalization [121 (111, 131) kcal/kg vs 111 (101, 119) kcal/kg, 3.4 (3.1, 3.8) g/kg vs 3.1 (2.8, 3.5) g/kg], IUGR group were more than non-IUGR group (P < 0.05).While the cumulative losses of energy [407 (360, 483) kcal/kg vs 448 (393, 527) kcal/kg, 534 (369, 689) kcal/kg vs 612 (453, 758) kcal/kg, 367 (12, 724) kcal/kg vs 718 (330, 996) kcal/kg, 381 (231, 609) kcal/kg vs 656 (394, 959) kcal/kg, 0 (0, 350) kcal/kg vs 387 (85, 826) kcal/kg] and
protein [12.3 (10.2, 15.5) g/kg vs 13.7 (11.7, 16.4) g/kg, 12.8 (7.8, 19.4) g/kg vs 17.5 (11.9, 22.7) g/kg, 6.2 (0, 22.6) g/kg vs 21.7 (7.3, 30.3) g/kg, 6.6 (1.8, 23.0) g/kg vs 22.1 (7.2, 32.5) g/kg, 1.9 (0, 16.7) g/kg vs 20.1 (0, 32.6) g/kg] were lower in IUGR group than in non-IUGR group at the same time (P < 0.05). (3) The mean daily growth rate to
body weight of non-EUGR group was higher than that of EUGR group [(12.7 ± 2.2) g/kg vs (10.3 ± 2.1) g/kg, P = 0.000]. The date beginning to feed [1.0 (1.0, 3.0) d vs 3.0 (2.0, 5.0) d], the total fasting time [3.0 (1.0, 5.5) d vs 4.0 (3.0, 9.0) d], the time to reach the lowest
body weight [4.0 (3.0, 6.0) d vs 6.0 (5.0, 8.0) d], and the time to restoring
birth weight [11.0 (9.0, 14.0) d vs 13.0 (10.0, 17.0) d], non-EUGR group were shorter than that of EUGR group (P < 0.05). The percentage of the infants who needed
ventilator therapy was lower in non-EUGR group than in EUGR group (70.4% vs 51.0%, P = 0.031). (4) The mean daily energy intake in postnatal time of 2 weeks [81 (70, 91) kcal/kg vs 73 (63, 85) kcal/kg] and the mean
protein intake daily in postnatal time of 1 week [1.6 (1.4, 2.0) g/kg vs 1.4 (1.1, 1.8) g/kg], 2 weeks [2.4 (2.1, 2.7) g/kg vs 2.1 (1.8, 2.6) g/kg] and before total
enteral nutrition [3.0 (2.5, 3.4) g/kg vs 2.7 (2.3, 3.1) g/kg] were higher in non-EUGR group than in EUGR group (P < 0.05).While the cumulative losses of energy in postnatal time of 2 weeks [546 (403, 707) kcal/kg vs 655 (494, 795) kcal/kg] and the cumulative losses of
protein in postnatal time of 1 week [13.1 (10.9, 15.1) g/kg vs 14.8 (12.0, 16.6) g/kg] and 2 weeks [15.5 (11.4, 19.8) g/kg vs 20.0 (12.1, 24.0) g/kg] were lower in non-EUGR group than in EUGR group (P < 0.05). (5) The incidence of
neonatal respiratory distress syndrome was lower in IUGR group than in non-IUGR group (34.9% vs 56.7%, P = 0.005); the incidence of hypertensive disorders in pregnancy (54.0% vs 24.2%, P = 0.000) and
fetal distress in uterus (25.4% vs 7.5%, P = 0.001)of the pregnant women were higher in IUGR group than in non-IUGR group. (6) The incidence of
septicemia of the newborn (11.3% vs 0%, P = 0.020) and the incidence of hypertensive disorders in pregnancy of the pregnant women (31.0% vs 14.3%, P = 0.036) in EUGR group were higher than in non-EUGR group.
CONCLUSION: