T cell non-Hodgkin's lymphoma with colesional mucormycosis presenting as palatal perforation: a case report.

Non-Hodgkin's lymphoma (NHL) is predominantly a disease of lymph nodes, but extranodal involvement is not very uncommon. Palatal involvement by NHL is rare. Mucormycosis is a devastating fungal infection commonly seen in immunocompromised individuals, including those with NHL, but it is affecting the same region has been reported very rarely. Simultaneous infiltration of hard palate by NHL and mucormycosis is extremely unusual. Herein we describe a patient who presented with palatal hole with histopathological examination revealing presence of lymphoma with colesional mucormycosis. The identification of mucor was vital because chemotherapy alone in the absence of antifungals would have had devastating consequences as the mortality of untreated mucormycosis is high.
AuthorsAfaq Ahmad Khan, Ambuj Garg, Shashi Dhawan, Pankaj Kumar Agarwal, Fouzia Siraj, Shyam Aggarwal
JournalJournal of the Indian Medical Association (J Indian Med Assoc) Vol. 110 Issue 7 Pg. 499-500 (Jul 2012) ISSN: 0019-5847 [Print] India
PMID23520681 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antifungal Agents
  • Vincristine
  • Amphotericin B
  • Doxorubicin
  • Cyclophosphamide
  • Prednisolone
  • Amphotericin B (therapeutic use)
  • Antifungal Agents (therapeutic use)
  • Antineoplastic Combined Chemotherapy Protocols (administration & dosage, therapeutic use)
  • Combined Modality Therapy
  • Cyclophosphamide (administration & dosage)
  • Debridement
  • Doxorubicin (administration & dosage)
  • Humans
  • Lymphoma, T-Cell (complications, diagnosis, pathology, therapy)
  • Male
  • Middle Aged
  • Mucormycosis (complications, diagnosis, pathology, therapy)
  • Nasal Cavity (pathology)
  • Opportunistic Infections (complications, diagnosis, pathology, therapy)
  • Palatal Neoplasms (complications, diagnosis, pathology, therapy)
  • Palate, Hard (pathology)
  • Prednisolone (administration & dosage)
  • Rhinitis (complications, diagnosis, pathology, therapy)
  • Vincristine (administration & dosage)

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