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Adenofibroma of the uterus: multiple recurrences following wide local excision.

Abstract
The uterine adenofibroma is a form of mixed mesodermal tumor in which both epithelial and stromal components are benign. A case is presented in which a patient with this lesion was treated with excision of the tumor rather than hysterectomy. Two years later, she developed a recurrence of the lesion, which was again treated with wide local excision. A hysterectomy was done 9 months later, and a polypoid lesion was noted in the fundus of the uterus which on histologic examination was thought to be potentially either an adenofibroma precursor or a maturation of the previous cellular adenofibroma. Since uterine adenofibroma usually occurs in older patients, the standard treatment has been hysterectomy. Because of this patient's age, she was initially treated with a more conservative approach. However, despite the fact that the uterine adenofibroma is a benign lesion, it has an obvious potential to recur when treated conservatively.
AuthorsV L Seltzer, A Levine, G Spiegel, D Rosenfeld, E L Coffey
JournalGynecologic oncology (Gynecol Oncol) Vol. 37 Issue 3 Pg. 427-31 (Jun 1990) ISSN: 0090-8258 [Print] United States
PMID2351327 (Publication Type: Case Reports, Journal Article)
Topics
  • Adenofibroma (pathology, surgery)
  • Adult
  • Endometriosis (pathology, surgery)
  • Fallopian Tubes (surgery)
  • Female
  • Humans
  • Hysterectomy
  • Neoplasm Recurrence, Local
  • Neoplasms, Multiple Primary
  • Ovariectomy (methods)
  • Uterine Neoplasms (pathology, surgery)
  • Uterus (pathology)

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