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Linezolid-induced serotonin syndrome.

Abstract
A young drug abuser was admitted to our intensive care unit for organophosphorus poisoning. He required mechanical ventilation and was started empirically on linezolid for suspected nosocomial infection. The patient developed high-grade fever with altered sensorium and clonus. Serotonin syndrome was suspected and the patient was started on cyproheptadine. He recovered within 3 days of withdrawing linezolide and administering cyproheptadine.
AuthorsVishal Gupta, Niteen D Karnik, Rushikesh Deshpande, Meenakshi Amit Patil
JournalBMJ case reports (BMJ Case Rep) Vol. 2013 (Mar 18 2013) ISSN: 1757-790X [Electronic] England
PMID23513014 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Acetamides
  • Anti-Infective Agents
  • Oxazolidinones
  • Linezolid
Topics
  • Acetamides (adverse effects)
  • Adult
  • Anti-Infective Agents (adverse effects)
  • Humans
  • Linezolid
  • Male
  • Oxazolidinones (adverse effects)
  • Serotonin Syndrome (chemically induced)

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