Antioxidant activity and physicochemical properties of an acidic polysaccharide from Morinda officinalis.

Abstract

An acidic polysaccharide APMO was isolated from Morinda officinalis by alkaline solvent extraction followed by fractionation treatments. Its antioxidant activities were evaluated by various methods in vitro, APMO presented excellent capability in scavenging DPPH radicals, chelating ferrous ions and inhibiting hemolysis of rats erythrocyte induced by H2O2, which was stronger than those of Vc at high concentration. Moreover, APMO displayed moderate reducing power. Physicochemical characteristics of APMO were observed by a combination of chemical and instrumental analysis. APMO predominantly consisted of galacturonic acid, arabinose and galactose. Galacturonic acid was assigned to be 1→4 glycosyl linkage in the skeleton of APMO.

• Authors: Hualin Zhang, Jun Li, Jingmin Xia, Sanqing Lin
• Journal: International journal of biological macromolecules (Int J Biol Macromol) Vol. 58 Pg. 7-12 (Jul 2013) ISSN: 1879-0003 [Electronic] Netherlands
• PMID: 23511058 (Publication Type: Journal Article)
• Copyright: Crown Copyright © 2013. Published by Elsevier B.V. All rights reserved.

Chemical References

• Biphenyl Compounds
• Free Radical Scavengers
• Free Radicals
• Hexuronic Acids
• Picrates
• Plant Extracts
• Polysaccharides
• Reducing Agents
• galacturonic acid
• Arabinose
• Hydrogen Peroxide
• 1,1-diphenyl-2-picrylhydrazyl
• Galactose

Topics

• Animals
• Arabinose (chemistry)
• Biphenyl Compounds (chemistry)
• Erythrocytes (drug effects)
• Free Radical Scavengers (chemistry, isolation & purification, pharmacology)
• Free Radicals (chemistry)
• Galactose (chemistry)
• Hemolysis
• Hexuronic Acids (chemistry)
• Hydrogen Peroxide (pharmacology)
• Male
• Morinda (chemistry)
• Oxidation-Reduction
• Picrates (chemistry)
• Plant Extracts (chemistry, isolation & purification, pharmacology)
• Polysaccharides (chemistry, isolation & purification, pharmacology)
• Rats
• Rats, Sprague-Dawley
• Reducing Agents (chemistry)