Influence of a metaphylactic treatment with Baycox(®) Bovis on the reproductive performances of Fresian heifers: a preliminary study.

A blind, randomised, controlled, multicentric field trial was conducted to assess the influence of a metaphylactic treatment with an oral solution of toltrazuril on some reproductive parameters of Italian Fresian heifers during the first 18-20 months of life. For this goal 40 calves were selected from two dairy farms and randomly divided into two homogeneous groups: MTol, treated with toltrazuril and NegC, left untreated. The calves were clinically and coprologically examined over the entire study period. The body condition scores, the body weights and the age at the first service were recorded and compared between the two groups, in addition to some other reproductive parameters including number of pregnancies, average service per pregnancy, conception rate, conception rate at first service and post first service conception rate. The analysis of the results showed that the metaphylactic treatment with toltrazuril influenced positively the average age of the first service (MTol 461.4 days versus NegC 485.45 days), the overall conception rate (MTol 95 % versus NegC 85 %), the success at first (MTol 60 % versus NegC 45 %) and second (MTol 75 % versus NegC 45 %) services and, consequently, the mean number of services to be carried out for each animal (MTol 1.4 ± 0.6 versus NegC 1.6 ± 0.79). Furthermore, the results confirmed that toltrazuril treatment, applied in accordance with the epidemiological aspects of each farm, is highly efficacious in persistent reduction of oocyst excretions with particular reference to Eimeria zuernii, Eimeria bovis, considered to be mainly responsible for clinical coccidiosis.
AuthorsFabrizia Veronesi, Lucio Nisoli, Manuela Diaferia, Roberto Falcini, Emanuele Ficola, Daniela Piergili Fioretti
JournalParasitology research (Parasitol Res) Vol. 112 Issue 6 Pg. 2137-42 (Jun 2013) ISSN: 1432-1955 [Electronic] Germany
PMID23504039 (Publication Type: Journal Article, Multicenter Study, Randomized Controlled Trial)
Chemical References
  • Coccidiostats
  • Triazines
  • toltrazuril
  • Administration, Oral
  • Animals
  • Cattle
  • Coccidiostats (administration & dosage)
  • Eimeria (isolation & purification)
  • Feces (parasitology)
  • Italy
  • Reproduction (drug effects)
  • Treatment Outcome
  • Triazines (administration & dosage)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: