Evaluation of Co-Q10 anti-gingivitis effect on plaque induced gingivitis: A randomized controlled clinical trial.

Abstract

BACKGROUND:

Deficiency of Co-Q10 has been found to be responsible for periodontal destruction; therefore, this study was undertaken to evaluate the anti-gingivitis effect of Co-Q10 on plaque induced gingivitis.

MATERIALS AND METHODS:

Thirty subjects with plaque induced gingivitis were enrolled in a split mouth randomized controlled trial. For each subject, scaling was randomly performed for any two quadrants, followed by the topical application of Co-Q10 randomly in a previously scaled and as an unscaled quadrant for a period of 28 days. Four treatment options were planned: option A: scaling only; option B: Co-Q10 along with scaling; option C: Co-Q10.

RESULTS:

Marked reduction in gingival, bleeding, and plaque scores were recorded at the sites where C0-Q10 was applied. Mean±S.D of aforementioned periodontal parameters at 28th day showed significant reduction for option A, B, and C when compared with baseline.

CONCLUSION:

Promising results were obtained after the solitary application of Co-Q10 as well as when it was used as an adjunct to scaling and root planing for treatment of plaque induced gingivitis.

• Authors: Anirban Chatterjee, Abhishek Kandwal, Nidhi Singh, Amit Singh
• Journal: Journal of Indian Society of Periodontology (J Indian Soc Periodontol) Vol. 16 Issue 4 Pg. 539-42 (Oct 2012) ISSN: 0972-124X [Print] India
• PMID: 23493408 (Publication Type: Journal Article)