The correlation between fetal bradycardia area in the second stage of labor and acidemia at birth.

Abstract

OBJECTIVE:

To quantify fetal bradycardia in the second stage of labor and to determine the threshold of the area that correlates with neonatal acidemia.

METHOD:

We analyzed the cardiotocograms of 33 women with single pregnancy and term spontaneous labor who presented fetal bradycardia in the second stage of labor. We retrospectively calculated the fetal bradycardia area in the last 60 min before delivery with an upper limit of 90 bpm and correlated the area with neonatal pH. The study of the regression line determined the cut-off threshold between fetal well-being and distress. Significance was set at p < 0.05.

RESULTS:

The linear correlation between the bradycardia area and neonatal pH indicate that increasing bradycardia area was correlated with significant pH decrease. The threshold value of the area indicative of severe acidemia was ≥ 12.72 cm(2) (Pearson r = -0.76, p < 0.002). The diagnostic accuracy of the test was 73%. The PPV = 78.5% and the NPV = 68.4%. With such a cut-off, the timing of acidemia can be calculated as 25 min for a fetal heart rate (FHR) of 80 bpm, 13 min for a FHR of 70 bpm, 8 min for a FHR of 60 bpm, 6 min for a FHR of 50 bpm and 5 min for a FHR of 40 bpm.

CONCLUSION:

The bradycardia area in the second stage of labor significantly correlates with an accurate timing of fetal acidemia. Regardless of the cause of the bradycardia, the time for intervention is often short, meaning that any available intervention may be ineffective in preventing acidemia or even injury.

• Authors: Andrea L Tranquilli, Alessandra Biagini, Pantaleo Greco, Mariarosaria Di Tommaso, Stefano R Giannubilo
• Journal: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (J Matern Fetal Neonatal Med) Vol. 26 Issue 14 Pg. 1425-9 (Sep 2013) ISSN: 1476-4954 [Electronic] England
• PMID: 23488805 (Publication Type: Journal Article)

Topics

• Acidosis (diagnosis, metabolism, physiopathology)
• Bradycardia (diagnosis, metabolism, physiopathology)
• Cardiotocography
• Female
• Fetal Distress (diagnosis, metabolism, physiopathology)
• Humans
• Labor Stage, Second (metabolism, physiology)
• Pregnancy
• Retrospective Studies
• Stress, Physiological