Interoperability of 300 watt and 150 watt xenon arc solar simulators in sun protection factor and in UVA protection factor clinical testing.

Abstract

BACKGROUND:

The purpose of these clinical trials was to determine if 300 W and 150 W xenon arc solar simulators (SSs) deliver the same sun protection factor (SPF) and UVA protection factor (PFA).

METHODS:

First, the SPF of the P7 control standard and of the P2 control standard was determined, testing 20 subjects using the method described in the Food and Drug Administration (FDA) Final Monograph and using 150 W and 300 W SSs. In the second clinical trial, the PFA of the Japanese Cosmetic Industry Association (JCIA) control standard and of the P2 control standard was determined, testing 10 subjects using the method described in the JCIA Technical Bulletin and using 150 W and 300 W SSs.

RESULTS:

The SPF values for P7 control standard determined using the 150 W and 300 W SSs were 4.54 ± 0.35 and 4.61 ± 0.32, respectively. The SPF values for P2 control standard determined using the 150 W and 300 W SSs were 17.0 ± 0.9 and 16.7 ± 0.9, respectively. The resultant PFA values for JCIA control standard determined using the 150 W and 300 W SSs were 4.06 ± 0.70 and 4.06 ± 0.70, respectively. The resultant PFA values for P2 control standard determined using the 150 W and 300 W SSs were 3.28 ± 0.25 and 3.44 ± 0.39, respectively.

CONCLUSION:

As the values are essentially identical for SPF and for PFA, the 150 W and 300 W SSs can be used interchangeably for SPF and PFA determinations.

• Authors: Alexa Martinez, Glenn Roberts, Katherine Garzarella, Michael Lutz, Michael Caswell
• Journal: Photodermatology, photoimmunology & photomedicine (Photodermatol Photoimmunol Photomed) Vol. 29 Issue 2 Pg. 78-83 (Apr 2013) ISSN: 1600-0781 [Electronic] England
• PMID: 23458391 (Publication Type: Controlled Clinical Trial, Journal Article)
• Copyright: © 2013 John Wiley & Sons A/S.

Chemical References

• Benzophenones
• Cinnamates
• Propiophenones
• Sunscreening Agents
• para-Aminobenzoates
• Xenon
• cinoxate
• oxybenzone
• avobenzone
• padimate-O

Topics

• Adult
• Benzophenones
• Cinnamates
• Equipment Design
• Female
• Humans
• Lighting (standards)
• Male
• Materials Testing
• Middle Aged
• Propiophenones
• Reference Standards
• Sun Protection Factor
• Sunlight
• Sunscreening Agents (standards)
• Ultraviolet Rays
• Xenon
• Young Adult
• para-Aminobenzoates