Abstract | PURPOSE: METHODS: Retrospective analysis of medical records of patients who received ATT for presumed ocular TB and completed at least 12 months follow-up after initiation of ATT. The diagnosis of presumed ocular TB was based on presence of ocular signs suggestive of TB, evidence of past tubercular infection, and exclusion of mimicking clinical entities. All patients received a combination of ATT and corticosteroid therapy. Primary outcome measure was progression (worsening) of ocular inflammation, defined as a two-step increase in level of inflammation (anterior chamber/ vitreous) or the appearance of new lesions following initiation of ATT. RESULTS: CONCLUSION: Progressive inflammation following ATT for presumed ocular TB is common. It generally resolves on escalation of corticosteroid therapy. Cases not responding to increased immunosuppression need to be re-investigated to rule out a nontubercular cause.
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Authors | S Basu, S Nayak, T R Padhi, T Das |
Journal | Eye (London, England)
(Eye (Lond))
Vol. 27
Issue 5
Pg. 657-62
(May 2013)
ISSN: 1476-5454 [Electronic] England |
PMID | 23449506
(Publication Type: Journal Article)
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Chemical References |
- Adrenal Cortex Hormones
- Antitubercular Agents
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Topics |
- Adolescent
- Adrenal Cortex Hormones
(therapeutic use)
- Adult
- Antitubercular Agents
(therapeutic use)
- Child
- Choroiditis
(epidemiology, etiology)
- Disease Progression
- Eye Diseases
(epidemiology, etiology)
- Female
- Humans
- Incidence
- India
(epidemiology)
- Inflammation
(epidemiology, etiology)
- Male
- Middle Aged
- Retinal Vasculitis
(epidemiology, etiology)
- Retrospective Studies
- Tuberculosis, Ocular
(complications, drug therapy)
- Uveitis
(epidemiology, etiology)
- Young Adult
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