Abstract | REASONS FOR PERFORMING STUDY: OBJECTIVES: To determine the number of hospitalised horses in 3 age groups that were selenium tested and the proportions of horses with categorised presenting clinical signs; the association/odds risk of final diagnosis with selenium deficiency and to examine the association between selenium status, vitamin E status and serum CK in adult horses. METHODS: Two hundred and seventy-one hospitalised horses with a selenium concentration evaluated between 1996 and 2011 were examined retrospectively. Records were examined in order to ascertain selenium and vitamin E concentrations, age, breed, gender, CK values, presenting clinical signs and final diagnosis. Data were analysed with proportions, Fisher's exact t test, odds ratios and multivariate linear regressions. RESULTS: Within the < 30 day old age group, 13/20 animals had low selenium concentrations. There were 18/42 horses in the 30 days to 2 years old age group with low selenium and 77/209 horses more than 2 years of age with low selenium. There was an association between low selenium and myopathy in the < 30-day-old animals (P = 0.017), all of which were classified as having WMD. No associations were identified between nutritional myopathy and selenium status in horses between 30 days and 2 years of age or in horses more than 2 years of age. CONCLUSIONS AND POTENTIAL RELEVANCE: This study indicates that WMD occurs most commonly in foals < 30 days old and is associated with low selenium concentrations (7 out of 8 affected foals had blood Selenium levels < 1.26 microm/l). Low serum selenium concentrations are common in hospitalised adult horses while nutritional myopathy is rare in these animals.
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Authors | R M Streeter, T J Divers, L Mittel, A E Korn, J J Wakshlag |
Journal | Equine veterinary journal. Supplement
(Equine Vet J Suppl)
Issue 43
Pg. 31-5
(Dec 2012)
United States |
PMID | 23447875
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Vitamin E
- Creatine Kinase
- Selenium
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Topics |
- Aging
- Animals
- Animals, Newborn
- Creatine Kinase
(blood)
- Female
- Horse Diseases
(blood, pathology)
- Horses
- Male
- Retrospective Studies
- Selenium
(blood, deficiency)
- Vitamin E
(blood)
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