[An ultrastructural and morphometric analysis of the polymorphonuclear leukocytes from lesion foci and from the peripheral blood in patients with a gonorrhea-chlamydial urogenital infection before and during treatment with doxycycline combined with T-activin].

Abstract

The leukocyte digestion function was decreased before therapy in the patients with combined gonorrheal-chlamydial infection. Tactivin therapy normalized the phagocytic activity of the peripheral blood polymorphonuclear leukocytes. These data give grounds for including tactivin in combined therapy of patients with mixed gonorrheal-chlamydial urogenital infection.

• Authors: V V Delektorskiĭ, E E Danielian, G N Iashkova, A A Kubanova, Kh M Khachikian
• Journal: Vestnik dermatologii i venerologii (Vestn Dermatol Venerol) Issue 2 Pg. 15-21 ( 1990) ISSN: 0042-4609 [Print] Russia (Federation)
• Vernacular Title: Ul'trastrukturnyĭ i morfometricheskiĭ analiz polimorfnoiadernykh leĭkotsitov ochagov porazheniia i perifericheskoĭ krovi bol'nykh gonoreĭno-khlamidiĭnoĭ urogenital'noĭ infektsieĭ do i v protsesse lecheniia doksitsiklinom v sochetanii s T-aktivinom.
• PMID: 2343663 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Adjuvants, Immunologic
• Peptides
• Thymus Extracts
• T-activin
• Doxycycline

Topics

• Adjuvants, Immunologic (therapeutic use)
• Chlamydia Infections (drug therapy, pathology)
• Chlamydia trachomatis
• Combined Modality Therapy
• Doxycycline (therapeutic use)
• Female
• Genital Diseases, Female (drug therapy, pathology)
• Gonorrhea (drug therapy, pathology)
• Humans
• Neutrophils (drug effects, ultrastructure)
• Peptides (therapeutic use)
• Phagocytosis (drug effects)
• Thymus Extracts (therapeutic use)
• Time Factors
• Urinary Tract Infections (drug therapy, pathology)