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Multiple biological properties of macelignan and its pharmacological implications.

Abstract
Macelignan found in the nutmeg mace of Myristica fragrans obtains increasing attention as a new avenue in treating various diseases. Macelignan has been shown to possess a spectrum of pharmacological activities, including anti-bacterial, anti-inflammatory, anti-cancer, anti-diabetes, and hepatoprotective activities; recently, it has also been shown to have neuroprotective activities. This review summarizes the current research on the biological effects of macelignan derived from M. fragrans, with emphasis on the importance in understanding and treating complex diseases such as cancer and Alzheimer's disease.
AuthorsSaswati Paul, Jae Kwan Hwang, Hahn Young Kim, Won Kyung Jeon, ChiHye Chung, Jung-Soo Han
JournalArchives of pharmacal research (Arch Pharm Res) Vol. 36 Issue 3 Pg. 264-72 (Mar 2013) ISSN: 1976-3786 [Electronic] Korea (South)
PMID23435944 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
Chemical References
  • Anti-Inflammatory Agents, Non-Steroidal
  • Antineoplastic Agents, Phytogenic
  • Antioxidants
  • Lignans
  • Neuroprotective Agents
  • Plant Extracts
  • macelignan
Topics
  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal (chemistry, pharmacology)
  • Antineoplastic Agents, Phytogenic (chemistry, pharmacology)
  • Antioxidants (chemistry, pharmacology)
  • Cell Survival (drug effects, physiology)
  • Humans
  • Lignans (chemistry, pharmacology)
  • Myristica
  • Neuroprotective Agents (chemistry, pharmacology)
  • Plant Extracts (chemistry, pharmacology)

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