Abstract | OBJECTIVES: METHODS: RESULTS: The incidence of upper limb thromboembolectomy was 3.3 per 100 000 person-years among men and 5.2 per 100 000 person-years among women; the risk of limb amputation, stroke and death after thromboembolectomy was increased. There was an increased risk of thromboembolectomy of the upper limb in patients with AF diagnosed with hypertension (hazard ratio [HR] 2.2-2.9), myocardial infarction (HR 2.9-3.9), heart failure (HR 1.6-1.9), and stroke (HR 2.2-3.8). For those diagnosed with diabetes mellitus, the risk was non-significantly increased by 1.2-1.4. Females had a 1.8-fold (95% confidence interval [CI] 1.5-2.3) fold increased risk of thromboembolectomy as compared with men. The risk reduction for systemic embolism with new OACs as compared with warfarin in patients with AF is similar to that seen with warfarin (odds ratio 0.79, 95% CI 0.38-1.64). CONCLUSIONS:
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Authors | L V Andersen, G Y H Lip, J S Lindholt, L Frost |
Journal | Journal of thrombosis and haemostasis : JTH
(J Thromb Haemost)
Vol. 11
Issue 5
Pg. 836-44
(May 2013)
ISSN: 1538-7836 [Electronic] England |
PMID | 23433284
(Publication Type: Journal Article, Meta-Analysis, Review, Systematic Review)
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Copyright | © 2013 International Society on Thrombosis and Haemostasis. |
Chemical References |
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Topics |
- Anticoagulants
(therapeutic use)
- Arm
(blood supply)
- Arteries
(pathology)
- Clinical Trials, Phase III as Topic
- Humans
- Prognosis
- Randomized Controlled Trials as Topic
- Risk Factors
- Thrombectomy
- Thromboembolism
(drug therapy, prevention & control, surgery)
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