Abstract |
Free-tissue transfer has become routine surgery because of standardization of instrumentation, techniques, and training. The incidence of microvascular thrombosis leading to free-flap failure is relatively low; however, anastomotic thrombosis can still occur despite the best of circumstances. Although majority of the time it is due to technical mishap or misjudgment, free-flap failure can occur due to intrinsic factors, such as the patient's increased propensity to develop clots. We describe a case report of a patient with malignancy and multiple thrombophilias, which led to 2 successive failures in microvascular flap transfer to restore abdominal domain. The aim o f this article is to increase awareness of the potential for thrombophilias to cause a dismal outcome in free-tissue transfer. A review of the literature will be presented, and published cases of free-flap failure in patients with thrombophilia(s) will be summarized.
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Authors | Krithika Srikanthan, Nisha Viswanathan, James C Yuen |
Journal | Annals of plastic surgery
(Ann Plast Surg)
Vol. 71
Issue 6
Pg. 675-81
(Dec 2013)
ISSN: 1536-3708 [Electronic] United States |
PMID | 23429221
(Publication Type: Case Reports, Journal Article, Review, Systematic Review)
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Topics |
- Free Tissue Flaps
(blood supply)
- Graft Survival
- Humans
- Male
- Middle Aged
- Postoperative Complications
(etiology, surgery)
- Thrombophilia
(complications)
- Thrombosis
(etiology, surgery)
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