Diabetes does not affect outcome of symptomatic carotid stenosis treated with endovascular techniques.

Abstract

BACKGROUND:

The influence of diabetes on carotid revascularization techniques is controversial, with few data regarding angioplasty and stenting (CAS). Our purpose was to analyze whether its presence constitutes a risk factor for poor outcome of patients with carotid stenosis treated with CAS.

METHODS:

We compared 30-day and long term morbidity and mortality, as well as restenosis rates, of non diabetic and diabetic patients with symptomatic carotid stenosis treated with endovascular techniques.

RESULTS:

318 consecutive patients, 116 (36.5%) of them diabetics, were followed for a median of 56 months. Cumulative 30-day stroke, ischemic cardiopathy and death rate was 4% for non diabetics and 5.2% for diabetics (non significant). Long term stroke and mortality rate was 26.4% for the first group and 34.3% for the second (non significant). The most frequent causes of death were myocardial infarction (17.5% non diabetics, 44% diabetics, p = 0.04), ischemic stroke (12.5% non diabetics, 4% diabetics, non significant) and cancer (30% non diabetics, 16% diabetics, non significant). Twelve patients (6.4%) had restenosis ≥ 50%, 5.9% non diabetic, 7.4% diabetic, also without statistical significance.

CONCLUSIONS:

In our series, endovascular treatment is both efficient and safe in diabetic patients with symptomatic carotid stenosis; therefore, the presence of diabetes mellitus did not increase the risks linked to CAS procedure.

• Authors: Aida Lago, Vera Parkhutik, Jose Ignacio Tembl, Ara Bermejo, Fernando Aparici, Esperanza Mainar, Víctor Vázquez-Añón
• Journal: European neurology (Eur Neurol) Vol. 69 Issue 5 Pg. 263-9 ( 2013) ISSN: 1421-9913 [Electronic] Switzerland
• PMID: 23429066 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2013 S. Karger AG, Basel.

Topics

• Adult
• Aged
• Aged, 80 and over
• Angioplasty (adverse effects)
• Carotid Stenosis (complications, mortality, surgery)
• Cause of Death
• Diabetes Mellitus (mortality, physiopathology, surgery)
• Endovascular Procedures (adverse effects)
• Female
• Humans
• Magnetic Resonance Imaging
• Male
• Middle Aged
• Myocardial Infarction (etiology, mortality)
• Retrospective Studies
• Risk Assessment
• Risk Factors
• Stroke (etiology, mortality)
• Treatment Outcome