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Central line associated blood stream infection related to cooling catheter in cardiac arrest survivors undergoing therapeutic hypothermia by endovascular cooling.

AbstractINTRODUCTION:
The risk of central line associated blood stream infections (CLABSI) related to cooling catheters used for therapeutic hypothermia (TH) is unclear.
METHODS:
We performed a retrospective analysis on 131 cardiac arrest survivors between 2007 and 2010, who underwent TH by femorally placed endovascular cooling catheter. All patients received prophylactic intravenous ampicillin-sulbactam for 72 hours to reduce the risk of aspiration pneumonia. Cooling catheter related CLABSI and other infections over a period of seven days from initiation of TH were estimated.
RESULTS:
Of a total 131 patients, 16 (12%) patients had bacteremia or infection prior to initiation of TH and were excluded. Of the remaining 115 (88%) patients, zero (0%) patients had cooling catheter related CLABSI and 23 (20%) patients had other infections during the study period.
CONCLUSION:
In cardiac arrest survivors undergoing TH, femorally placed endovascular cooling catheter is not associated with an increased incidence of CLABSI.
AuthorsNishant Patel, Sanjeev U Nair, Pampana Gowd, Ankur Gupta, David Morris, Giovanni G Geronilla, Justin Lundbye
JournalConnecticut medicine (Conn Med) Vol. 77 Issue 1 Pg. 35-41 (Jan 2013) ISSN: 0010-6178 [Print] United States
PMID23427372 (Publication Type: Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • sultamicillin
  • Ampicillin
  • Sulbactam
Topics
  • Aged
  • Ampicillin (administration & dosage)
  • Anti-Bacterial Agents (administration & dosage)
  • Catheter-Related Infections (drug therapy, etiology)
  • Catheterization, Central Venous (adverse effects, methods)
  • Cross Infection (drug therapy, etiology)
  • Endovascular Procedures
  • Female
  • Heart Arrest (therapy)
  • Humans
  • Hypothermia, Induced (methods)
  • Male
  • Middle Aged
  • Retrospective Studies
  • Sepsis (drug therapy, etiology)
  • Sulbactam (administration & dosage)

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