Abstract | OBJECTIVE: DESIGN: Prospective, population-based, register study. SETTING: Denmark, 1996-2007. POPULATION: METHODS: Treated women were routinely recommended to have follow-up with annual smears for at least 5 years. MAIN OUTCOME MEASURES: Using individually linked nationwide register data on conizations and follow-up tests (smears and biopsies), we calculated the cumulative proportion of treated women undergoing the recommended follow-up. We measured this cumulative proportion conservatively in 15-month intervals for 5 years. RESULTS: Adherence to annual follow-up among 45,984 treated women decreased gradually. In total, 90% of these women obtained at least one smear in the first post-treatment year, but only 40% obtained the recommended tests for 5 years. Five-year adherence was substantially better outside the capital area, for example, the odds ratio for women from Jutland compared with women from the capital area was 1.70 (95% confidence interval 1.60-1.82). CONCLUSIONS: Adherence to follow-up after conization was poor in Denmark. Our findings suggest that because of this poor adherence, recommendations for long-term annual follow-up after treatment of cervical intraepithelial neoplasia may not be highly effective. Shorter follow-up schedules using highly sensitive tests appear attractive.
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Authors | Sidsel S Barken, Elsebeth Lynge, Erik S Andersen, Matejka Rebolj |
Journal | Acta obstetricia et gynecologica Scandinavica
(Acta Obstet Gynecol Scand)
Vol. 92
Issue 7
Pg. 852-7
(Jul 2013)
ISSN: 1600-0412 [Electronic] United States |
PMID | 23418941
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © 2013 The Authors Acta Obstetricia et Gynecologica Scandinavica © 2013 Nordic Federation of Societies of Obstetrics and Gynecology. |
Topics |
- Adult
- Cervix Uteri
(surgery)
- Conization
- Denmark
- Early Detection of Cancer
(statistics & numerical data)
- Female
- Follow-Up Studies
- Humans
- Logistic Models
- Middle Aged
- Odds Ratio
- Patient Compliance
(statistics & numerical data)
- Prospective Studies
- Registries
- Uterine Cervical Neoplasms
(diagnosis, surgery)
- Vaginal Smears
(statistics & numerical data)
- Uterine Cervical Dysplasia
(diagnosis, surgery)
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