LeGoo polymer injection into hydatid cyst would eliminate intraoperative spillage of scolices.

Abstract

BACKGROUND:

Hydatid disease is caused by the tapeworm Echinococcus granulosus or Echinococcus multilocularis or Echinococcus Vogeli. It is the most severe helminthic zoonosis, with a major medical, social, and economic burden in endemic areas such as the Mediterranean region, South America, Australia, Turkey, New Zealand, Alaska, Canada, and the Middle East. The cornerstone in the management of hydatid cysts is surgery, and its recurrence is due mainly to the spillage of hydatid scolices rich fluid into the surrounding tissues.

AIM:

In this study, we test a polymer benefit in intraoperative scolices spillage prevention, this polymer is called LeGoo.

METHODS:

The LeGoo polymer was used here in vivo animal's hydatid cysts and in vitro hydatid cysts excised from human beings.

RESULT:

Microscopic examination of the aspirated fluid from human being and sheep hydatid cysts before LeGoo injection showed numerous alive scolices. All sheep lung hydatid cysts with LeGoo injection transformed into a solid gelatinous mass, microscopic examination of the content swabs showed no scolices. LeGoo polymer injection into human hydatid cysts in vitro changed them into a solid gelatinous mass that can be mobilized easily with negative swabs for scolices.

• Authors: Fadhil Al-Amran, Hayder M Abdulnabi
• Journal: General thoracic and cardiovascular surgery (Gen Thorac Cardiovasc Surg) Vol. 61 Issue 4 Pg. 218-22 (Apr 2013) ISSN: 1863-6713 [Electronic] Japan
• PMID: 23417855 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• LeGoo
• Poloxamer

Topics

• Animals
• Echinococcosis (therapy)
• Echinococcosis, Pulmonary (diagnostic imaging, therapy)
• Echinococcus
• Humans
• Poloxamer
• Radiography
• Sheep