Botulinum toxin type A in chronic plantar fasciitis: clinical effects one year after injection.

Abstract

OBJECTIVE:

To determine whether the efficacy of botulinum toxin type A in chronic plantar fasciitis was maintained for more than six months after treatment.

DESIGN:

Observational follow-up study.

SUBJECTS:

Twenty-four patients who received botulinum toxin type A injection in a previous randomized study of chronic plantar fasciitis (active treatment group) and who presented a benefit one month after treatment.

METHODS:

A visual analogue scale for pain and the Foot Health Status Questionnaire were used to re-evaluate results 12 months after the botulinum toxin injection. No further injections of botulinum toxin had been administered during the follow-up period. Patients were also asked to give a subjective assessment of treatment outcome.

RESULTS:

At 12 months, compared with the six-month evaluation, there was a further improvement in foot pain measured using the visual analogue scale, though this did not reach significance (1.78 at 6 months versus 1.22 at 12 months; P = 0.142). However, there were significant improvements in two domains of Foot Health Status Questionnaire: foot pain (91.11 at 6 months versus 80.00 at 12 months; P = 0.001) and foot function (96.19 at 6 months versus 89.38 at 12 months; P = 0.047). There was a small, non-significant deterioration in the shoe and foot health domains. Satisfaction with the outcome was good or very good in the large majority of patients.

CONCLUSIONS:

In patients with chronic plantar fasciitis, the positive effect detected six months after treatment with botulinum toxin type A was maintained at 12 months and there was a further improvement in pain and foot function.

• Authors: Ismael V Díaz-Llopis, Diego Gómez-Gallego, Francisco J Mondéjar-Gómez, Alfredo López-García, Jose M Climent-Barberá, Carmen M Rodríguez-Ruiz
• Journal: Clinical rehabilitation (Clin Rehabil) Vol. 27 Issue 8 Pg. 681-5 (Aug 2013) ISSN: 1477-0873 [Electronic] England
• PMID: 23411793 (Publication Type: Journal Article)

Chemical References

• Neuromuscular Agents
• Botulinum Toxins, Type A

Topics

• Botulinum Toxins, Type A (administration & dosage, therapeutic use)
• Chronic Disease
• Fasciitis, Plantar (drug therapy)
• Female
• Follow-Up Studies
• Humans
• Injections
• Male
• Middle Aged
• Neuromuscular Agents (administration & dosage, therapeutic use)
• Pain (drug therapy)
• Pain Measurement
• Randomized Controlled Trials as Topic
• Treatment Outcome